Ghostbusters: Afterlife (internationally known as Ghostbusters: Legacy) is an upcoming American fantasy comedy film directed by Jason Reitman and written by Reitman and Gil Kenan. It stars Mckenna Grace, Finn Wolfhard, Carrie Coon, Paul Rudd, Logan Kim, Celeste O'Connor, Oliver Cooper and Bokeem Woodbine, while Bill Murray, Dan Aykroyd, Ernie Hudson, Sigourney Weaver and Annie Potts reprise their roles from the original films. It is the direct sequel to Ghostbusters (1984) and Ghostbusters II (1989) and the fourth film, overall, in the Ghostbusters franchise. Set 30 years after Ghostbusters II, the story follows a family moving to a small town, where they learn more about their family's connection and the town's secrets.

A third Ghostbusters film had been in various stages of development since Ghostbusters II in 1989. After Murray refused to commit to the project, and after the death of cast member Harold Ramis in 2014, Sony instead produced a reboot. After the film underperformed at the box office, Reitman began developing a direct sequel to the original films. The new cast members were announced by July 2019, while the members from the original films signed on two months later.

Ghostbusters: Afterlife is scheduled for release in the United States on July 10, 2020, by Columbia Pictures through Sony Pictures Releasing.